[摘要] 通过传统中医和复杂系统的非线性科学以及系统生物学等新兴学科相结合，整理总结800余篇关于通心络基础与临床研究提出通络治疗血管病变的整合效应机制即系统效应——提高机体自适应、自调节、自修复能力，最终达到自稳状态，同时对通络治疗血管病变系统效应中的几个关键问题进行深入讨论。[关键词]系统效应；血管病变；整合效应机制；自适应；自调节；自修复[Abstract] Through the combination of the traditional Chinese medicine and the newly emerging no-linear science of complex systemitic and system biology, suggest that the integrate effects mechanism of curing vascular disease by removing obstruction in luos, namely system effectiveness——improve the ability of self- adaptation , self-regulation, self-repair, achieve homeostasis stability by arrange more than 800 thesis about basis and clinical research of Tongxinluo ,at the same time carry out thorough discussion about the system effectiveness of curing collateral-vasc